Culture PCR Species Risk Factors Site Empiric Therapy Targeted Therapy Surgery IFD Final Response Patient alive Year of Infection
Lichtheimia corymbifera Cancer (AML), Chemotherapy, Neutropenia Deep soft tissues, Skin Posaconazole, Amphotericin B lipid complex Surgical debridement of necrotic tissue from ulcers (right leg) - repeatedly Partial Response No 2008
Culture available Lichtheimia corymbifera Immunosuppression, Cancer (CML), Hematopoietic stem cell transplantation (HSCT) Lungs Liposomal amphotericin B, Caspofungin Partial Response Yes 2009
Culture available Lichtheimia corymbifera Immunosuppression, Cancer Other (Multiple Myeloma), Hematopoietic stem cell transplantation (HSCT), ICU Lungs Liposomal amphotericin B, Posaconazole Deterioration or failure No 2008
Lichtheimia corymbifera ICU, Trauma, Corticosteroids Gastrointestinal tract Fluconazole Liposomal amphotericin B, Voriconazole, Posaconazole solution Ileocolectomy Complete Response Yes 2007
Lichtheimia corymbifera Corticosteroids, Alcoholism, Solid organ transplantation Biliary system Liposomal amphotericin B Resection Complete Response Yes 2008
Culture available Lichtheimia corymbifera Diabetes mellitus, Solid organ transplantation Bones, Paranasal sinus(es) Liposomal amphotericin B Functional endoscopic sinus surgery (FESS) Complete Response Yes 2007
Lichtheimia corymbifera Trauma Deep soft tissues, Skin Liposomal amphotericin B, Posaconazole Complete Response Yes 2007
Lichtheimia corymbifera Cancer (ALL), Chemotherapy Lungs Liposomal amphotericin B Liposomal amphotericin B, Voriconazole, Posaconazole , Caspofungin Lobectomy (middle, right) Complete Response Yes 2007
Culture available Lichtheimia corymbifera Solid organ transplantation Lungs Posaconazole Thoracotomy and resection of lesions, decortication Complete Response Yes 2007
Culture available Lichtheimia corymbifera Cancer (ALL), Chemotherapy Lungs Liposomal amphotericin B, Posaconazole Lobectomy Complete Response Yes 2007
Lichtheimia corymbifera Corticosteroids, Immunosuppression, Cancer (ALL), Chronic pulmonary disease, Hematopoietic stem cell transplantation (HSCT) Lungs Caspofungin, Liposomal amphotericin B Lobectomy Deterioration or failure No 2005
Culture available Lichtheimia corymbifera Diabetes mellitus Deep soft tissues Amphotericin B deoxycholate, Itraconazole Wound debridement Complete Response Yes 2006
Lichtheimia corymbifera Corticosteroids, ICU, Major surgery Gastrointestinal tract, Other: Abdominal drainage infection Caspofungin, Liposomal amphotericin B Stable Disease No 2007
Culture available Lichtheimia corymbifera Diabetes mellitus Lungs, Other: Right ear Amphotericin B deoxycholate, Amphotericin B lipid complex Complete Response Yes 2010
Lichtheimia corymbifera Corticosteroids, Immunosuppression, Cancer Other (Aplastic Anemia), Chemotherapy, Hematopoietic stem cell transplantation (HSCT), Neutropenia Deep soft tissues, Liver, Lungs, Spleen Caspofungin, Voriconazole, Amphotericin B lipid complex Amphotericin B lipid complex, Voriconazole, Posaconazole , Fluconazole, Caspofungin Non-anatomic pulmonary lobectomy for abscess Stable Disease No 2009
Lichtheimia corymbifera Corticosteroids, Cancer (ALL), Chemotherapy, ICU, Neutropenia CNS, Gastrointestinal tract, Kidneys, Liver, Lungs, Spleen, Other: Large vessels Deterioration or failure No 2010
Lichtheimia corymbifera Cancer (CLL), Chemotherapy, Neutropenia Kidneys, Liver, Lungs, Spleen, Other: Thyroid Liposomal amphotericin B, Posaconazole Puncture of thyroid abscess Stable Disease No 2010
Lichtheimia corymbifera Corticosteroids, Immunosuppression, Cancer (CML), Hematopoietic stem cell transplantation (HSCT) Lungs Caspofungin, Itraconazole Liposomal amphotericin B, Caspofungin, Posaconazole Stable Disease Yes 2009
Lichtheimia corymbifera Corticosteroids, Cancer (CML), Chemotherapy, Neutropenia Eyes, Paranasal sinus(es), Other: Eyelids Posaconazole , Amphotericin B lipid complex Deterioration or failure No 2010
Lichtheimia corymbifera Cancer (CLL), Chemotherapy, Neutropenia Bones, Paranasal sinus(es) Liposomal amphotericin B Deterioration or failure No 2012
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Principle Investigator:
Prof. Oliver A. Cornely, MD, FACP, FIDSA, FAAM, FECMM, Cologne, Germany
Project Manager:
Danila Seidel, PhD, Cologne, Germany
Coordinating physician:
Maria J. G. T. Vehreschild, MD, Cologne, Germany
Epidemiology & Statistics:
J. Janne Vehreschild, MD, FECMM, Cologne, Germany